Les équipes


Publications récentes


Marcel V, Catez F, Diaz JJ. Ribosomes: the future of targeted therapies? Oncotarget. 2013 Oct;4(10):1554-5.

Marcel V, Ghayad SE, Belin S, Therizols G, Morel AP, Solano-Gonzàlez E, Vendrell JA, Hacot S, Mertani HC, Albaret MA, Bourdon JC, Jordan L, Thompson A, Tafer Y, Cong R, Bouvet P, Saurin JC, Catez F, Prats AC, Puisieux A, Diaz JJ. p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer. Cancer Cell. 2013 Sep 9;24(3):318-30.

Stirbat TV, Mgharbel A, Bodennec S, Ferri K, Mertani HC, Rieu JP, Delanoë-Ayari H. Fine tuning of tissues' viscosity and surface tension through contractility suggests a new role for α-catenin. PLoS One. 2013;8(2):e52554.

Dacheux E, Vincent A, Nazaret N, Combet C, Wierinckx A, Mazoyer S, Diaz JJ, Lachuer J, Venezia ND. BRCA1-Dependent Translational Regulation in Breast Cancer Cells. PLoS One. 2013 Jun 21;8(6):e67313.


Terrier O, Moules V, Carron C, Cartet G, Frobert E, Yver M, Traversier A, Wolff T, Riteau B, Naffakh N, Lina B, Diaz JJ, Rosa-Calatrava M. The influenza fingerprints: NS1 and M1 proteins contribute to specific host cell ultrastructure signatures upon infection by different influenza A viruses. Virology. 2012 Oct

Delloye-Bourgeois C, Goldschneider D, Paradisi A, Therizols G, Belin S, Hacot S, Rosa-Calatrava M, Scoazec JY, Diaz JJ, Bernet A, Mehlen P. Nucleolar localization of a netrin-1 isoform enhances tumor cell proliferation. Sci Signal. 2012 Aug 7;5(236):ra57.

Greco A, Arata L, Soler E, Gaume X, Couté Y, Hacot S, Callé A, Monier K, Epstein AL, Sanchez JC, Bouvet P, Diaz JJ. Nucleolin interacts with US11 protein of herpes simplex virus 1 and is involved in its trafficking. J Virol. 2012


Nguyen-Lefebvre AT, Gonin-Giraud S, Scherl A, Arboit P, Granger L, Sanchez JC, Diaz JJ, Gandrillon O, Madjar JJ. Identification of human, rat and chicken ribosomal proteins by a combination of two-dimensional polyacrylamide gel electrophoresis and mass spectrometry. J Proteomics. 2011 Feb 1;74(2):167-85.

Terrier O, Josset L, Textoris J, Marcel V, Cartet G, Ferraris O, N'Guyen C, Lina B, Diaz JJ, Bourdon JC and Rosa-Calatrava M. Cellular transcriptional profiling in human lung epithelial cells infected by different subtypes of influenza A viruses reveals an overall down-regulation of the host p53 pathway. Virol. J. 2011 Jun 8;8(1):285.

Chiesa J, Ferrer C, Arnould C, Vouyovitch CM, Diaz JJ, Gonzalez S, Mares P, Morel G, Wu Z-S, Zhu T, Lobie PE. and Mertani HC.Autocrine proliferative effects of hGH are maintained in primary cultures of human mammary carcinoma cells. J Clin Endoc Metab 2011, 96(9):

Auclair J, Vaissière T, Desseigne F, Lasset C, Bonadona V, Giraud S, Saurin JC, Joly MO, Leroux D, Faivre L, Audoynaud C, Montmain G, Ruano E, Herceg Z, Puisieux A, Wang Q. Intensity-dependent constitutional MLH1 promoter methylation leads to early onset of colorectal cancer by affecting both alleles. Genes Chromosomes Cancer. 2011 Mar;50(3):178-85.

El Fajoui, Z., Toscano, F., Jacquemin, G., Abello, J., Scoazec, J.Y., Micheau, O., Saurin, J.COxaliplatin Sensitizes Human Colon Cancer Cells to TRAIL through JNK-Dependent Phosphorylation of BclxL, Gastroenterology, 141, 663-673, (2011).


Hacot S, Coute Y, Belin S, Albaret MA, Mertani HC, Sanchez JC, Rosa-Calatrava M, Diaz JJ. Isolation of nucleoli. Curr Protoc Cell Biol.2010 Jun;Chapter 3:Unit3.36.

Belin, S., Kindbeiter, K., Hacot, S., Albaret, MA., Roca-Martinez, JX., Thérizols, G., Grosso., O. & Diaz., J-J. Uncoupling ribosome biogenesis regulation from RNA polymerase I activity during herpes simplex type 1 infection. RNA, 16, 131-140 (2010).

Josset L, Textoris J, Loriod B, Ferraris O, Moules V, Lina B, N'Guyen C, Diaz JJ, Rosa-Calatrava M. Gene Expression Signature-Based Screening Identifies New Broadly Effective Influenza A. PLoS ONE 5(10): e13169 (2010).

Belin S, Hacot S, Daudignon L, Therizols G, Pourpe S, Mertani HC, Rosa-Calatrava M, Diaz JJ. Purification of ribosomes from human cell lines. Curr Protoc Cell Biol. 2010 Dec;Chapter 3:Unit 3.40.


Juban, G., Giraud, G., Guyot, B., Belin, S., Diaz, J-J., Starck, J., Guillouf, C., Moreau-Gachelin, F. & Morlé, F. Spi-1 and Fli-1 directly activate common target genes involved in ribosome biogenesis in Friend erythroleukemic cells. Mol Cell Biol, 29, 2852-64 (2009).

Belin, S., Beghin, A., Solano-Gonzàlez, E., Laurent Bezin, L., Brunet-Manquat, S., Textoris, J., Prats, A-C., Mertani, H.M., Charles Dumontet, C. & Diaz, J-J. Dysregulation of Ribosome Biogenesis and Translational Capacity Is Associated with Tumor Progression of Human Breast Cancer Cells. PLoS ONE 4(9): e7147 (2009).

Beghin, A., Belin, S., Sleiman, RH., Brunet-Manquat, S., Goddard, S., Tabone, E., Treilleux, I., Poupon, MF., Diaz, J-J. & Charles Dumontet.ADP Ribosylation Factor Like 2 (Arl2) Regulates Breast Tumor Aggressivity in Immunodeficient Mice. PLoS ONE, 2009, 4(10): e7478.


Coute, Y., Kindbeiter, K., Belin, S., Dieckmann, R., Duret, L., Bezin, L., Sanchez, J. C. & Diaz, J. J. ISG20L2, a novel vertebrate nucleolar exoribonuclease involved in Ribosome biogenesis. Mol Cell Proteomics7, 546-59 (2008).

Callé, A., Ugrinova, I., Epstein, A.L., Bouvet, P., Diaz, J-J. & Greco, A. Nucleolin is required for an efficient herpes simplex virus type 1 infection. J. Virol82, 4762-73 (2008).

Diaz, J-J., Couderc, C., Couté, Y., Poncet, G., Pourpe, S., Hacot, S., Borson-Chazot, F., Aguerra, K., Scoazec, JY., Sanchez, JC. & Roche, C. A proteomic approach of the endocrine tumors. Annales d’Endocrinologie, 69, 138-142 (2008)


Couté, Y., Burgess, J.A., Diaz, J-J., Chichester, C., Lisacek, F., Greco, A. & Sanchez, J-C. Deciphering the human nucleolar proteome. Mass Spectrom Rev25, 215-34 (2006).)