Les équipes


Kfoury A, Virard F, Renno T, Coste I. Dual function of MyD88 in inflammation and oncogenesis : implications for therapeutic intervention. Curr Opin Oncol. 2014 Jan;26(1):86-91

Dejeans N, Manié S, Hetz C, Bard F, Hupp T, Agostinis P, Samali A, Chevet E. Addicted to secrete-novelconcepts and targets in cancer therapy. Trends Mol Med.2014 Jan 20. pii: S1471-4914(13)00213-X

Pacheco Y, Calender A, Valeyre D, Lebecque S. Role of T lymphocyte cyclic nucleotides and G protein in sarcoidosis. Rev Mal Respir. 2013 Oct;30(8):644-56

Kfoury A, Le Corf K, El Sabeh R, Journeaux A, Badran B, Hussein N, Lebecque S, Manié S, Renno T, Coste I. MyD88 in DNA repair and cancer cell resistance to genotoxic drugs. J Natl Cancer Inst. 2013 Jul 3;105(13):937-46

Tagoug I, Jordheim LP, Herveau S, Matera EL, Huber AL, Chettab K, Manié S, Dumontet C.Therapeutic enhancement of ER stress by insulin-like growth factor I sensitizes myeloma cells to proteasomal inhibitors. Clin Cancer Res. 2013 Jul 1;19(13):3556-66.

Huber AL, Lebeau J, Guillaumot P, Pétrilli V, Malek M, Chilloux J, Fauvet F, Payen L, Kfoury A, Renno T, Chevet E, Manié SN. p58(IPK)-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose. Mol Cell. 2013 Mar 28;49(6):1049-59

Toscano F, Estornes Y, Virard F, Garcia-Cattaneo A, Pierrot A, Vanbervliet B, Bonnin M, Ciancanelli MJ, Zhang SY, Funami K, Seya T, Matsumoto M, Pin JJ, Casanova JL, Renno T, Lebecque S. Cleaved/associated TLR3 represents the primary form of the signaling receptor. J Immunol. 2013 Jan 15;190(2):764-73

Estornes Y, Toscano F, Virard F, Jacquemin G, Pierrot A, Vanbervliet B, Bonnin M, Lalaoui N, Mercier-Gouy P, Pachéco Y, Salaun B, Renno T, Micheau O, Lebecque S. dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8. Cell Death and Differentiation. 2012 Sep;19(9):1482-94

Malek M, Guillaumot P, Huber A-L, Lebeau J, Pétrilli V, Kfoury A, Mikaelian I, Renno T, Manie S. LAMTOR1 depletion induces p53-dependent apoptosis via aberrant lysosomal activation. Cell Death Dis. 2012.

De Falco V, Tamburrino A, Ventre S, Castellone MD, Malek M, Manié SN, Santoro M. CD44 Proteolysis Increases CREB Phosphorylation and Sustains Proliferation of Thyroid Cancer Cells. Cancer Res. 2012 Mar 15;72(6):1449-58. 

Goutagny N, Estornes Y, Hasan U, Lebecque S, Caux C. Targeting pattern recognition receptors in cancer immunotherapy. Target Oncol. 2012 Mar;7(1):29-54