13 February 2014
The next CRCL/CLB seminar will take place Friday the 11th of september. Have a nice summer break !
Memorial Jurg Tschopp & SSORL/SSAI Meeting Montreux 27 & 28-29 April 2016
18 May 2015
Memorial Jürg Tschopp - Symposium
Organisation Departement of Biochemistry, University of Lausanne
Music & Convention Center, Montreux, Switzerland, April 27 2016
For more information: www.imk.ch/ssorl-ssai2016
2e International Symposium of the CRCL
26 March 2015
Congress Centre of Lyon, 21-23 september 2015
To register and submit an abstract (deadline 27 May): click here
Cell Cycle and Cancer Congress - 7 to 10 April 2015 Marseille
03 February 2015
The Cell Cycle and Cancer Congress is an international annual event organized by the French Society of Cell Biology. The 4th edition is scheduled in Marseille (France) 7 to 10 April 2015 and will be held at the prestigious Villa Méditerranée.
Congress and conference in oncology - EACR
11 March 2013
You can find on the EACR website various congresses, symposiums or workshops in the field of oncology research. More information: click here
2014 national calls
02 January 2013
Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function
18 November 2014
In the context of the nucleotide-binding domain and leucine rich repeat pyrin containing 1b (NLRP1b) inflammasome activation by anthrax lethal toxin, we reveal a new role for full-length caspase-1. The work of Baptiste Guey in Dr Virginie Petrilli team directly demonstrates that the caspase-1 45-kDa zymogen is able to process pro–IL-1β and to induce pyroptosis, and that apoptosis-associated speck-like protein containing a CARD is dis- pensable for the activity of the NLRP1b inflammasome. This is in contrast to the NLRP3 inflammasome activity, which is inhibited in the absence of caspase-1 autoproteolyis. Our data, which highlight differential requirements for caspase-1 autoproteolysis in NLRP1b and NLRP3 inflammasome function, may have implications for pathogen recognition and response.