Estornes Y, Toscano F, Virard F, Jacquemin G, Pierrot A, Vanbervliet B, Bonnin M, Lalaoui N, Mercier-Gouy P, Pachéco Y, Salaun B, Renno T, Micheau O, Lebecque S. dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8. Cell Death and Differentiation. In Press.
Malek M, Guillaumot P, Huber A-L, Lebeau J, Pétrilli V, Kfoury A, Mikaelian I, Renno T, Manie S. LAMTOR1 depletion induces p53-dependent apoptosis via aberrant lysosomal activation. Cell Death Dis. 2012 ; in press.
De Falco V, Tamburrino A, Ventre S, Castellone MD, Malek M, Manié SN, Santoro M. CD44 Proteolysis Increases CREB Phosphorylation and Sustains Proliferation of Thyroid Cancer Cells. Cancer Res. 2012 Mar 15;72(6):1449-58.
Guillaumot P, Luquain C, Malek M, Huber AL, Brugière S, Garin J, Grunwald D, Régnier D, Pétrilli V, Lefai E, Manié SN. 2010. Pdro, a protein associated with late endosomes and lysosomes and implicated in cellular cholesterol homeostasis. PLoS One. 5(6):e10977.
Coste I, Le Corf K, Kfoury A, Hmitou I, Druillennec S, Hainaut P, Eychene A, Lebecque S, Renno T. 2010. Dual function of MyD88 in RAS signalling and inflammation, leading to cell transformation. J. Clin Invest. 120: 3663-7.
Coste I, Freund JN, Spaderna S, Brabletz T, Renno T. 2007. Precancerous lesions upon sporadic activation of beta-catenin in mice. Gastroenterology 132: 1299-1308.
Perrot I, Blanchard D, Freymond N, Isaac S, Guibert B, Pachéco Y, Lebecque S. 2007. Dendritic cells infiltrating human non-small cell lung cancer are blocked at immature stage. J Immunol 178: 2763-2769.
Salaun B, Coste I, Rissoan MC, Lebecque SJ, Renno T. 2006. TLR3 can directly trigger apoptosis in human cancer cells. J Immunol 176: 4894-4901.