Principales publications
Uchuya-Castillo J, Aznar N, Frau C, Martinez P, Le Nevé C, Marisa L, Penalva LOF, Laurent-Puig P, Puisieux A, Scoazec JY, Samarut J, Ansieau S, Plateroti M.
Increased expression of the thyroid hormone nuclear receptor TRα1 characterizes intestinal tumors with high Wnt activity.
Oncotarget. 2018 Jul 24;9(57):30979-30996.
Ducheix S, Peres C, Härdfeldt J, Frau C, Mocciaro G, Piccinin E, Lobaccaro JM, De Santis S, Chieppa M, Bertrand-Michel J, Plateroti M, Griffin JL, Sabbà C, Ntambi JM, Moschetta A.
Deletion of Stearoyl-CoA Desaturase-1 From the Intestinal Epithelium Promotes Inflammation and Tumorigenesis, Reversed by Dietary Oleate.
Gastroenterology. 2018 Nov;155(5):1524-1538.
Cambuli FM, Correa BR, Rezza A, Burns SC, Qiao M, Uren PJ, Kress E, Boussouar A, Galante PA, Penalva LO, Plateroti M.
A Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and Stemness. Stem Cells, 2015. [Epub ahead of print] PMID: 26303183
Sirakov M, Boussouar A, Kress E, Frau C, Lone IN, Nadjar J, Angelov D, Plateroti M. The thyroid hormone nuclear receptor TRα1 controls the Notch signaling pathway and cell fate in murine intestine. Development, 2015. 142(16):2764-74. PMID: 26286942
Ozmadenci D, Féraud O, Markossian S, Kress E, Ducarouge B, Gibert B, Ge J, Durand I, Gadot N, Plateroti M, Bennaceur-Griscelli A, Scoazec JY, Gil J, Deng H, Bernet A, Mehlen P, Lavial F. Netrin -1 regulates somatic cell reprogramming and pluripotency maintenance. Nat Commun, 2015. 8;6:7398. PMID: 26154507
Lapierre M, Bonnet S, Bascoul-Mollevi C, Ait-Arsa I, Jalaguier S, Del-Rio M, Plateroti M, Roepman P, Ychou M, Pannequin J, Hollande F, Parker M, Cavailles V. The transcriptional coregulator RIP140 increases APC gene expression and controls intestinal homeostasis and tumorigenesis. J. Clin. Invest, 2014. 1;124(5):1899- 913. PMID: 24667635
Cambuli FM, Rezza A, Nadjar J. and Plateroti M. Musashi1-eGFP mice, a new tool for differential isolation of the intestinal stem cell populations. Stem Cells, 2013. 31(10), 2273-8. PMID: 23712573
Diala I, Wagner N, Magdinier F, Shkreli M, Sirakov M, Bauwens S, Schluth-Bolard C, Simonet T, Renault VM, Ye J, Djerbi A, Pineau P, Choi J, Artandi S, Dejean A, Plateroti M. and Gilson E. Telomere protection and TRF2 expression are modulated by the canonical Wnt signaling pathway. EMBO Rep, 2013. 14(4), 356-63. PMID: 23429341
Rezza A, Skah S, Roche C, Nadjar J, Samarut J and Plateroti M. The overexpression of the putative gut stem cell marker Musashi1 induces tumorigenesis through Wnt and Notch activation. Journal of Cell Science, 2010. 123(Pt 19):3256-65. PMID: 20826465
Kowalik MA, Perra A, Pibiri M, Cocco MT, Samarut J, Plateroti M, Ledda-Columbano GM, Columbano A. TRa is the critical thyroid hormone receptor isoform in T3-induced proliferation of hepatocytes and pancreatic acinar cells. Journal of Hepathology, 2010. 53(4):686-92. PMID: 20638743
Kress E, Skah S, Sirakov M, Nadjar J, Gadot N, Scoazec JY, Samarut J and Plateroti M. Cooperation between the Thyroid hormone Receptor TRa1 and the WNT pathway in the induction of intestinal tumorigenesis. Gastroenterology, 2010. 138(5):1863-74. PMID: 20114049
Kress E, Rezza A, Nadjar J, Samarut J and Plateroti M. The Frizzled related sFRP2 gene is a target of the TR1 thyroid hormone receptor and activates the -catenin signaling in intestinal epithelial progenitors. J. Biol. Chem, 2009. 284: 1234-1241.
Reviews invitées
Skah S., Uchuya-Castillo J., Sirakov M., Plateroti M. (2017). The thyroid hormone nuclear receptors and the Wnt/b-catenin pathway: An intriguing liaison. Dev. Biol. 422(2):71-82
Frau C, Godart M, Plateroti M. Thyroid hormone regulation of intestinal epithelial stem cell biology. (Invited review). Mol. Cell Endocrinol. 2017 Dec 25;459:90-97.
Perra A., Plateroti M., Columbano A. (2016). T3/TR axis in hepatocellular carcinoma: new concepts for an old pair. Endocr. Relat. Cancer 23(8):R353-69.
Sirakov M., Kress E., Nadjar J., Plateroti M. The thyroid hormones and their nuclear receptors: new players in intestinal epithelium stem cell biology? Cell Mol Life Sci, 2014. 71(15), 2897-907. PMID: 24604390
Sirakov M, Plateroti M. The thyroid hormones and their nuclear receptors in the gut: from developmental biology to cancer. Biochim Biophys Acta, 2011. 1812(8):938-46. PMID: 21194566