Nous sommes heureux d’accueillir, le vendredi 24 septembre à 11h30, Jeremie Poschmann (Center for research in transplantation and immunology, Nantes) à l’occasion d’un webinaire intitulé :
Epigenomic and transcriptomic profiling to characterize disease mechanisms in immuno-pathologies
My interest lies in the application of discovery research, i.e., hypothesis free large-scale data analyses in patient cohorts to identify molecular patterns which are associated to disease state. For this I have developed functional genomics, such as histone ChIP-seq and (single cell) transcriptomics and have used them to generate novel hypotheses of pathophysiological mechanisms, reveal unique disease signatures and characterize new candidate genes. Throughout my talk I will illustrate how we use this discovery approach and uncovered disease mechanisms in neurological and immune diseases. At last, I will draw parallels to similar applications in cancer research.
Bio:
Jeremie Poschmann (CRCN INSERM) established his research group “functional genomics of immuno-pathologies” at the Center for research in transplantation and immunology in 2017 where he also setup the single cell genomics platform. Before, JP was a genomics specialist at the Exeter Sequencing Service and a post-doc at the Genome Institute Singapore. He has authored 21 original articles, notably in Cell, Nature Immunology and Nature Methods