The proinflammatory secretome of senescent cells can be controlled by a HIF2A-dependent upregulation and a FURIN-dependent cleavage of the ANGPTL4 secreted factor
Makulyte G, Safwan-Zaiter H, Goehrig D, Huna A, Mangelinck A, Mikawa T, Palazzo A, Moudombi L, Medard JJ, Chanal M, Lecot P, Michallet MC, Gavard J, Adnot S, Dubus P, Kondoh H, Mann C, Tan NS, Bertolino P, Flaman JM, Bernard D.